Microbiopsy for real-time PCR biomarker profiling

Background

We supported a clinical trial which aimed to validate the use of microbiopsy sampling for real-time PCR for biomarker profiling in facial skin. The trial sought to understand gene expression patterns related to skin aging and sun damage, providing a molecular-level view of facial skin health.

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Objective

To demonstrate the feasibility and effectiveness of using microbiopsy for real-time PCR biomarker profiling, generating insights into the molecular mechanisms of skin aging and the effects of sun damage.

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Approach

Leveraging extensive early-stage clinical trial expertise, we provided strategic guidance on:

• designing a trial to validate the combined techniques of microbiopsy and real-time PCR
• navigating regulatory pathways to ensure compliance with industry standards
• implementing innovative minimally invasive skin sampling tools in real-world healthcare settings whilst addressing practical challenges.

Results

• Successful validation of the use of microbiopsy for real-time PCR biomarker profiling.
• Identification of gene expression patterns associated with skin aging and sun damage, offering new insights into facial skin health.
• Demonstration of the feasibility of microbiopsy techniques for clinical and research applications.

Key takeaways

• Our expertise enabled the successful design and execution of a trial that combined a number of cutting-edge skin profiling techniques.
• Validation of microbiopsy for biomarker profiling opens new avenues for understanding and treating skin aging.
• The trial demonstrated the practical implementation of innovative technologies in real-world settings.